Tuesday, June 09, 2009

Chronic Fatigue and Fibromyalgia Syndromes

The Root Cause of CFS/FMS Is Typically "Bad" Molecules

CFS/FMS is typically caused by "bad" molecules that bind to good molecules inside the body and subsequently inhibit their function. Sounds simple? It is very simple conceptually. However, there are many bad and many good molecules, and tracking them is hard work. This is not for the faint of heart. We define "bad molecule" rather loosely as a molecule that can take an internal biochemical system down. The good molecules typically involve:

* enzymes (chemical that converts one chemical to another chemical)
* neurotransmitters (sends a message from one nerve to another)
* neurotransmitter receptors (the area of a nerve that receives message)
* hormones (chemical used to control a processes within the body)
* cofactors (ingredient used to make a chemical)
* cells in the immune system (when these go down; bacteria, virus, and fungi go up)
* cells and parts of cells such as the cell membrane and mitochondria

The bad molecules are typically:

* heavy metals such as lead, mercury, cadmium, nickel, silver, tin and barium
* natural and synthetic chemicals and poisons (e.g. carbon monoxide, drugs)
* pesticides (e.g. DDT)
* natural toxins such as H2S (i.e. hydrogen sulfide, that results when fungi and bad bacteria in gut ferment sugar).
* toxins resulting from natural waste products produced by the body that are not filtered out properly (e.g. free radicals that cause "oxidation" of "good" molecules).

Damage to enzymes due to bad molecules is a MAJOR issue since enzymes are used to regulate and synthesize MANY processes in the body. If a tiny bad molecule binds to a big enzyme molecule, it can take it down. Enzymes have a defense system to guard against this from occurring (e.g. thiols), yet if those defenses go down for a short period of time, the enzyme can go down, and sometimes permanently. Enzymatic damage is a BIG issue with CFS/FMS.

Problems caused by genes (i.e. a pathology that runs in a family) are similar. Each gene produces a protein (all genes do this). And a bad gene (one that messes you up) typically binds to something good and alters its function, in a manner similar to that which is done by a bad molecule such as a heavy metal or a pesticide.

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